Article
Adjuvant action of Escherichia coli enterotoxin for delayed-type hypersensitivity to Oka vaccine virus on pernasal co-administration in mice.
Vaccine - 22 Nov 2000
Sasaki K, Asano Y, Honma Y, Kamiya N, Handa T, Ichinose Y, Yokochi T, Shiraki K, Tsuji T
Abstract excerpt
The usefulness of a mutant of Escherichia coli enterotoxin for the induction of cellular immunity to varicella-zoster virus as a mucosal adjuvant is assessed in mice. When a commercially available live varicella vaccine (the Oka strain) and toxin were once administered simultaneously via the nasal route, delayed-type hypersensitivity to Oka vaccine virus was significantly induced and detected by footpad test in...
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