Article
V3 sequence analysis and biological characterization of HIV-1 isolates from asymptomatic and early symptomatic Tanzanian individuals.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Sept 2000
Holm-Hansen C, Stern B, Rustad S, Shao J, Asjö B
Abstract excerpt
The aim of this study was to determine HIV-1 V3 sequences, in vitro biological characteristics and co-receptor usage of virus isolates from Tanzania. Virus was isolated from 14 of 17 samples investigated. Four of the isolates induced syncytia in MT-2 cells and used the CXCR4 co-receptor, while the remaining 10 isolates used the CCR5 co-receptor characteristic of non-MT-2 tropic viruses. One of the four MT-2...
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