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Article

Association of apolipoprotein E polymorphism to clinical heterogeneity of multiple sclerosis.

Neuroscience letters - 22 Dec 2000

Ballerini C, Campani D, Rombolà G, Gran B, Nacmias B, Amato M P, Siracusa G, Bartolozzi L, Sorbi S, Massacesi L

Abstract excerpt

In this study we investigated the distribution of apolipoprotein E (APO E) genotypes in sporadic multiple sclerosis (MS) cases and in normal controls. Later onset of chronic progressive MS was observed in patients carrying the epsilon2 allele, whereas APO E alleles were found at similar frequency in MS and in the control population. These findings indicate that clinical heterogeneity, but probably not...

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Source

Identifiers

PMID: 11109009
DOI: 10.1016/s0304-3940(00)01646-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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