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Article

Modeling the HLA component in rheumatoid arthritis: sensitivity to DRB1 allele frequencies.

Genetic epidemiology - 1 Dec 2000

Tézenas du Montcel S, Reviron D, Genin E, Roudier J, Mercier P, Clerget-Darpoux F

Abstract excerpt

Rheumatoid arthritis is an inflammatory disease for which positive associations have been described with some HLA-DRB1 alleles. The associated alleles share a similar amino acid sequence in the third hypervariable region, the shared epitope, but differ at position 71 and 86. It has been suggested that HLA susceptibility to rheumatoid arthritis could be due not only to the shared epitope but could also be...

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Share to Amino Acid Sequence
Share to Arthritis, Rheumatoid
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Histocompatibility Testing

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Share to Models, Genetic

Source

Identifiers

PMID: 11108650
DOI: 10.1002/1098-2272(200012)19:4<422::AID-GEPI12>3.0.CO;2-A

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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