Article
Ascertainment issues in variance components models.
Genetic epidemiology - 1 Dec 2000
de Andrade M, Amos C I
Abstract excerpt
One of the main concerns in the family studies of complex diseases is the effect that ascertainment and correction for it may have on test procedures and estimators. Elston and Sobel [1979] and Hopper and Mathews [1982] proposed two ways to correct for ascertainment in the study of quantitative trait data. For single ascertainment, using a variance components approach, we present results of simulation studies...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.