Article
Identification of antigenic epitopes on the foot and mouth disease virus isolate O1/Manisa/Turkey/69 using monoclonal antibodies.
Revue scientifique et technique (International Office of Epizootics) - 1 Dec 2000
Aktas S, Samuel A R
Abstract excerpt
A panel of mouse monoclonal antibodies (MAbs) was produced against a strain of type O foot and mouth disease virus (FMDV) from the Middle East, O1/Manisa/Turkey/69. Seven neutralising MAbs were fully characterised and all were found to react with conformational epitopes. Monoclonal antibody neutralisation-resistant mutants (MARMs) were generated from the parental virus stock and the complete capsid sequences of...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Antigens, Viral
- Enzyme-Linked Immunosorbent Assay
- Epitope Mapping
- Epitopes
- Foot-and-Mouth Disease Virus
- Hybridomas
- Image Processing, Computer-Assisted
