Article
Genetic basis of antigenic variation in foot-and-mouth disease serotype A viruses from the Middle East.
Vaccine - 23 Jan 2014
Upadhyaya Sasmita, Ayelet Gelagay, Paul Guntram, King Donald P, Paton David J, Mahapatra Mana
Abstract excerpt
Foot-and-mouth disease viruses (FMDV) from serotype A exhibit high antigenic diversity. Within the Middle East, a strain called A-Iran-05 emerged in 2003, and subsequently replaced the A-Iran-96 and A-Iran-99 strains that were previously circulating in the region. Viruses from this strain did not serologically match with the established A/Iran/96 vaccine, although most early samples matched with the older...
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