Article
[Sporadic upper urinary tract urothelial cell carcinomas: identification of interaction between toxic carcinogens and individuals genetic susceptibility].
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie - 1 Jan 2010
Colin P, Koenig P, Ballereau C, Phé V, Berthon N, Villers A, Biserte J, Rouprêt M
Abstract excerpt
Upper urinary tract urothelial cell carcinomas (UUT UCC) are rare sporadic tumors. Recent epidemiologic and molecular data have shown a singular susceptibility of UUT UCCs for specific risk factors. The main exogenic factors involved in UUT UCCs carcinogenesis remain tobacco and occupational exposure (aromatic amines, polycyclic hydrocarbures and chlored solvents). Enzymatic variants of detoxification system may...
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