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Article

Evidence for a cytoskeleton attachment domain at the N-terminus of the NF2 protein.

Journal of neuroscience research - 15 Dec 2000

den Bakker M A, Riegman P H, Suurmeijer A P, Vissers C J, Sainio M, Carpen O, Zwarthoff E C

Abstract excerpt

Neurofibromatosis type 2 is a hereditary cancer syndrome characterized by the development of bilateral vestibular schwannomas. Underlying the disease are inactivating mutations of the NF2 tumor suppressor gene, located on chromosome 22, encoding a 595-amino-acid protein. The NF2 protein, also known as merlin or schwannomin, is reported to act as a membrane-cytoskeleton linking protein. This assumption is based on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11107160
DOI: 10.1002/1097-4547(20001215)62:6<764::AID-JNR2>3.0.CO;2-V

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence for a cytoskeleton attachment domain at the N-terminus of the NF2 protein.PMID 11107160Read ↗

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Detection of cellular proteins that interact with the NF2 tumor suppressor gene product.Semantic proximity Read ↗

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