Article
Transplanted fetal striatum in Huntington's disease: phenotypic development and lack of pathology.
Proceedings of the National Academy of Sciences of the United States of America - 5 Dec 2000
Freeman T B, Cicchetti F, Hauser R A, Deacon T W, Li X J, Hersch S M, Nauert G M, Sanberg P R, Kordower J H, Saporta S, Isacson O
Abstract excerpt
Neural and stem cell transplantation is emerging as a potential treatment for neurodegenerative diseases. Transplantation of specific committed neuroblasts (fetal neurons) to the adult brain provides such scientific exploration of these new potential therapies. Huntington's disease (HD) is a fatal, incurable autosomal dominant (CAG repeat expansion of huntingtin protein) neurodegenerative disorder with primary...
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