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Article

Lack of association between adult asthma and the tumour necrosis factor alpha-308 polymorphism gene.

The European respiratory journal - 1 Oct 2000

Louis R, Leyder E, Malaise M, Bartsch P, Louis E

Abstract excerpt

Tumour necrosis factor (TNF)alpha is a cytokine endowed with potent inflammatory properties that may contribute to airway inflammation in asthma. It has previously been shown that the single base pair polymorphism-308 (G to A substitution) in the promoter of TNFalpha gene results in enhanced cytokine secretion. Whether this polymorphism is associated with the presence of phenotypic expression of asthma is...

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Source

Identifiers

PMID: 11106199
DOI: 10.1034/j.1399-3003.2000.16d06.x

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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