Article
Plasticity of the urothelial phenotype: effects of gastro-intestinal mesenchyme/stroma and implications for urinary tract reconstruction.
Differentiation; research in biological diversity - 1 Oct 2000
Li Y, Liu W, Hayward S W, Cunha G R, Baskin L S
Abstract excerpt
The present study tests the hypothesis that heterotypic stromal-epithelial interactions cause phenotypic changes in urothelium. The rational for the experimental design is to simulate heterotypic stromal-epithelial interactions that are created at the anastomotic site of intestinal-bladder augmentations and internal urinary diversions where the urothelium is in direct contact with the gastro-intestinal tract...
Topics
- Animals
- Animals, Newborn
- Cell Differentiation
- Cell Transplantation
- Fetal Tissue Transplantation
- Immunohistochemistry
- Keratins
- Membrane Glycoproteins
- Mesoderm
- Mice
- Mice, Inbred BALB C
- Mucins
- Phenotype
- Rats
