Article
B cells in rheumatoid arthritis.
Arthritis research - 1 Jan 2000
Kim H J, Berek C
Abstract excerpt
Normally the immune response is restricted to the peripheral secondary lymphoid organs. However, additional ectopic lymphoid tissue may develop at chronic sites of inflammation. In the synovium of rheumatoid arthritis patients the local production of proinflammatory cytokines seems to support the formation of a precisely structured microenvironment, which allows an antigen dependent immune response to take place....
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