Article
The role of T cells in rheumatoid arthritis.
Archivum immunologiae et therapiae experimentalis - 1 Jan 2000
Weyand C M, Bryl E, Goronzy J J
Abstract excerpt
In rheumatoid arthritis (RA), T cells infiltrate into the synovial membrane where they initiate and maintain activation of macrophages and synovial fibroblasts, transforming them into tissue-destructive effector cells. The diversity of the disease process and the formation of complex lymphoid microstructures indicate that multiple T cell activation pathways are involved. This model is supported by the association...
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