Article
Activation of c-Jun N-terminal kinase and activator protein 1 by receptor activator of nuclear factor kappaB.
Molecular pharmacology - 1 Dec 2000
Lee Z H, Kwack K, Kim K K, Lee S H, Kim H H
Abstract excerpt
Receptor activator of nuclear factor kappaB (RANK), a lately identified member of the tumor necrosis factor receptor superfamily, plays important roles both in osteoclastogenesis and in lymph node development. Previously, we and others showed that RANK could stimulate the activity of c-Jun N-terminal kinase (JNK). In this study, we investigated the mechanism by which RANK activates JNK. We found that N-terminal...
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