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Article

T cell receptor usage of virus-specific CD8 cells and recognition of viral mutations during acute and persistent hepatitis B virus infection.

European journal of immunology - 1 Nov 2000

Maini M K, Reignat S, Boni C, Ogg G S, King A S, Malacarne F, Webster G J, Bertoletti A

Abstract excerpt

T cells specific for a single viral epitope, but using different T cell receptors, should have flexibility in their epitope recognition to protect the infected host against the emergence of viral escape mutants. Therefore, polyclonality of the hepatitis B virus (HBV)-specific cytotoxic T lymphocyte response has been hypothesized to be a major determinant in the control of infection. We analyzed the Vbeta chain...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to CD8-Positive T-Lymphocytes

Share to Cytotoxicity, Immunologic

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Share to Hepatitis B, Chronic

Share to Receptors, Antigen, T-Cell

Source

Identifiers

PMID: 11093121
DOI: 10.1002/1521-4141(200011)30:11<3067::AID-IMMU3067>3.0.CO;2-L

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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