Article
Origin of Plasmodium falciparum malaria is traced by mitochondrial DNA.
Molecular and biochemical parasitology - 1 Nov 2000
Conway D J, Fanello C, Lloyd J M, Al-Joubori B M, Baloch A H, Somanath S D, Roper C, Oduola A M, Mulder B, Povoa M M, Singh B, Thomas A W
Abstract excerpt
The origin and geographical spread of Plasmodium falciparum is here determined by analysis of mitochondrial DNA sequence polymorphism and divergence from its most closely related species P. reichenowi (a rare parasite of chimpanzees). The complete 6 kb mitochondrial genome was sequenced from the single known isolate of P. reichenowi and from four different cultured isolates of P. falciparum, and aligned with the...
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