Article
Plasmodium falciparum accompanied the human expansion out of Africa.
Current biology : CB - 27 Jul 2010
Tanabe Kazuyuki, Mita Toshihiro, Jombart Thibaut, Eriksson Anders, Horibe Shun, Palacpac Nirianne, Ranford-Cartwright Lisa, Sawai Hiromi, Sakihama Naoko, Ohmae Hiroshi, Nakamura Masatoshi, Ferreira Marcelo U, Escalante Ananias A, Prugnolle Franck, Björkman Anders, Färnert Anna, Kaneko Akira, Horii Toshihiro, Manica Andrea, Kishino Hirohisa, Balloux Francois
Abstract excerpt
Plasmodium falciparum is distributed throughout the tropics and is responsible for an estimated 230 million cases of malaria every year, with a further 1.4 billion people at risk of infection. Little is known about the genetic makeup of P. falciparum populations, despite variation in genetic diversity being a key factor in morbidity, mortality, and the success of malaria control initiatives. Here we analyze a...
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