Article
The origins of African Plasmodium vivax; insights from mitochondrial genome sequencing.
PloS one - 1 Jan 2011
Culleton Richard, Coban Cevayir, Zeyrek Fadile Yildiz, Cravo Pedro, Kaneko Akira, Randrianarivelojosia Milijaona, Andrianaranjaka Voahangy, Kano Shigeyuki, Farnert Anna, Arez Ana Paula, Sharp Paul M, Carter Richard, Tanabe Kazuyuki
Abstract excerpt
Plasmodium vivax, the second most prevalent of the human malaria parasites, is estimated to affect 75 million people annually. It is very rare, however, in west and central Africa, due to the high prevalence of the Duffy negative phenotype in the human population. Due to its rarity in Africa, previous studies on the phylogeny of world-wide P. vivax have suffered from insufficient samples of African parasites....
Topics
- Africa
- Base Sequence
- Genetic Variation
- Genome, Mitochondrial
- Haplotypes
- Humans
- Madagascar
- Molecular Sequence Data
- Nucleotides
- Phylogeny