Error-Prone Candidates Vie for Somatic Mutation

Abstract excerpt

Antibodies play a major role in the resistance of higher organisms to disease. This is made possible because mice, humans, and other species have evolved three unusual molecular mechanisms that allow the generation of an enormously diverse repertoire of antibodies from a relatively small amount of genetic material. First, each antibody-forming B cell assembles different combinations of variable (V), diversity...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to CRISPR and Genetic Engineering
• Share to Monoclonal and Polyclonal Antibodies Research
• Share to T-cell and B-cell Immunology