Article
[Association between interleukin-8 gene-251 locus polymorphism and respiratory syncytial virus bronchiolitis and post-bronchiolitis wheezing in infants].
Zhonghua er ke za zhi = Chinese journal of pediatrics - 1 Nov 2007
Tian Man, Zhao De-yu, Wen Guan-yu, Shi Sheng-yun, Chen Rong-hua
Abstract excerpt
OBJECTIVE: Respiratory syncytial virus (RSV) infects nearly all children under two years of age. It is not understood why some develop serious bronchiolitis. Whether there is a genetic component is not known. The nature of the association between RSV bronchiolitis and subsequent wheezing remains unknown. interleukin-8 (IL-8) is a potent neutrophil chemokine and activator, which plays a role in virus-induced...
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