Article

The functional genetics of respiratory syncytial virus induced bronchiolitis : an investigation into the transcriptional regulation of IL8 and LTA

2004-01-01

Abstract excerpt

This thesis explores the extent to which natural variation in DNA sequence may influence the transcriptional regulation of genes that play a critical role in the immune response to infection. As a model system we began by examining Interleukin-8 (<i>IL-8</i>) as it has been implicated in the pathogenesis of a very common infection namely, RSV-induced bronchiolitis. Previously, we have described an association betw...

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Literature Corpus work: 80669f55-4667-52aa-a3ef-325642e36160
DOI: 10.21954/ou.ro.0000fa11

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