Article
Increased in vivo transcription of an IL-8 haplotype associated with respiratory syncytial virus disease-susceptibility.
Genes and immunity - 1 Jun 2004
Hacking D, Knight J C, Rockett K, Brown H, Frampton J, Kwiatkowski D P, Hull J, Udalova I A
Abstract excerpt
Interleukin-8 (IL-8) has been implicated in the pathogenesis of RSV-induced bronchiolitis. Previously, we have described an association between bronchiolitis disease severity and a specific IL-8 haplotype comprising six single-nucleotide polymorphisms (SNPs) (-251A/+396G/+781T/+1238delA/+1633T/+2...
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