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Article

Efficient DNA base excision repair in ataxia telangiectasia cells.

European journal of biochemistry - 1 Dec 2000

Cappelli E, Rossi O, Chessa L, Frosina G

Abstract excerpt

Ataxia telangiectasia (A-T) cells are sensitive to a broad range of free-radical-producing and alkylating agents. Damage caused by such agents is in part repaired by base excision [base excision repair (BER)]. Two BER pathways have been demonstrated in mammalian cells: a single-nucleotide-insertion pathway and a long-patch pathway involving resynthesis of 2-10 nucleotides. Although early studies failed to detect...

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Source

Identifiers

PMID: 11082200
DOI: 10.1046/j.1432-1033.2000.01789.x

Genes

ATM
BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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