Article
The extracellular calcium-sensing receptor dimerizes through multiple types of intermolecular interactions.
The Journal of biological chemistry - 16 Feb 2001
Zhang Z, Sun S, Quinn S J, Brown E M, Bai M
Abstract excerpt
Recent studies have shown that the G protein-coupled, extracellular calcium ([Ca(2+)](o))-sensing receptor (CaR) forms disulfide-linked dimers through cysteine residues within its extracellular domain and that dimerization of the CaR has functional implications. In this study, we have investigated which of these disulfide linkages are essential for dimerization of the CaR and whether they are required for these...
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