Article
The let-60 locus controls the switch between vulval and nonvulval cell fates in Caenorhabditis elegans.
Genetics - 1 Dec 1990
Han M, Aroian R V, Sternberg P W
Abstract excerpt
During induction of the Caenorhabditis elegans hermaphrodite vulva by the anchor cell of the gonad, six multipotent vulval precursor cells (VPCs) have two distinct fates: three VPCs generate the vulva and the other three VPCs generate nonspecialized hypodermis. Genes that control the fates of the VPCs in response to the anchor cell signal are defined by mutations that cause all six VPCs to generate vulval tissue...
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