The Caenorhabditis elegans EGL-26 protein mediates vulval cell morphogenesis.

doi:10.1006/dbio.2001.0514

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Article

The Caenorhabditis elegans EGL-26 protein mediates vulval cell morphogenesis.

Developmental biology - 15 Jan 2002

Hanna-Rose Wendy, Han Min

Abstract excerpt

In screens for Caenorhabditis elegans mutants defective in vulval morphogenesis, we isolated multiple mutants in which the uterus and the vulva fail to make a functional connection, resulting in an egg-laying defective phenotype. Two of these connection of gonad defective (Cog) mutants carry alleles of the egl-26 gene. We demonstrate that vulval lineages in egl-26 mutant animals are normal, but one vulval cell,...

Topics

Amino Acid Sequence
Animals
Animals, Genetically Modified
Base Sequence
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cell Lineage
Cell Size
DNA-Binding Proteins
Disorders of Sex Development
Female
Genes, Helminth
Genes, Recessive
Helminth Proteins
Molecular Sequence Data
Morphogenesis
Mosaicism
Phenotype

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Open in PubMed

Identifiers

PMID: 11784109
DOI: 10.1006/dbio.2001.0514

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