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Polydom: a secreted protein with pentraxin, complement control protein, epidermal growth factor and von Willebrand factor A domains

7 Nov 2000

Abstract excerpt

To identify extracellular proteins with epidermal growth factor (EGF) domains that are potentially involved in the control of haemopoiesis, we performed degenerate reverse-transcriptase-mediated PCR on the murine bone-marrow stromal cell line MS-5 and isolated a new partial cDNA encoding EGF-like domains related to those in the Notch proteins. Cloning and sequencing of the full-length cDNA showed that it encoded...

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PMID: 11062057
DOI: 10.1042/bj3520049

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