Article
The emerging Janus face of SVEP1 in development and disease.
Trends in molecular medicine - 1 Nov 2023
Elenbaas Jared S, Jung In-Hyuk, Coler-Reilly Ariella, Lee Paul C, Alisio Arturo, Stitziel Nathan O
Abstract excerpt
Sushi, von Willebrand factor type A, EGF, and pentraxin domain containing 1 (SVEP1) is a large extracellular matrix protein that is also detected in circulation. Recent plasma proteomic and genomic studies have revealed a large number of associations between SVEP1 and human traits, particularly chronic disease. These include associations with cardiac death and disease, diabetes, platelet traits, glaucoma,...
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