Neuropilins: a versatile partner of extracellular molecules that regulate development and disease.

Abstract excerpt

Neuropilins are a vertebrate-specific family of membrane multidomain proteins. They are crucial for the embryonic development of neural and vascular systems, whereas in the adult organism they are implicated in many processes, such as angiogenesis and the immune response. Additionally, it has been shown that they are overexpressed in numerous types of tumours, which results in higher microvessel density and...

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