Article
Isolation, characterization and mapping of the mouse and human PRG4 (proteoglycan 4) genes.
Cytogenetics and cell genetics - 1 Jan 2000
Ikegawa S, Sano M, Koshizuka Y, Nakamura Y
Abstract excerpt
PRG4 (proteoglycan 4) has been identified as megakaryocyte stimulating factor and articular superficial zone protein. PRG4 has characteristic motifs including somatomedin B and hemopexin domains, a chondroitin sulfate-attachment site and mucin-like repeats. During a screen of genes implicated in ectopic ossification, we found a novel mouse gene highly homologous to human and bovine PRG4 genes. Here, we report...
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