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Article

Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling.

Circulation research - 14 Apr 2017

Morooka Nanami, Futaki Sugiko, Sato-Nishiuchi Ryoko, Nishino Masafumi, Totani Yuta, Shimono Chisei, Nakano Itsuko, Nakajima Hiroyuki, Mochizuki Naoki, Sekiguchi Kiyotoshi

Abstract excerpt

RATIONALE: Lymphatic vasculature constitutes a second vascular system essential for immune surveillance and tissue fluid homeostasis. Maturation of the hierarchical vascular structure, with a highly branched network of capillaries and ducts, is crucial for its function. Environmental cues mediate the remodeling process, but the mechanism that underlies this process is largely unknown. OBJECTIVE: Polydom (also...

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PMID: 28179430
DOI: 10.1161/CIRCRESAHA.116.308825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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