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Article

Molecular characterization of guinea pig-adapted variants of Ebola virus.

Virology - 10 Nov 2000

Volchkov V E, Chepurnov A A, Volchkova V A, Ternovoj V A, Klenk H D

Abstract excerpt

Serial passage of initially nonlethal Ebola virus (EBOV) in outbred guinea pigs resulted in the selection of variants with high pathogenicity. Nucleotide sequence analysis of the complete genome of the guinea pig-adapted variant 8mc revealed that it differed from wild-type virus by eight mutation...

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PMID: 11062045
DOI: 10.1006/viro.2000.0572

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11062045-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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