Article
Abnormal synaptic organization between granule cells and Purkinje cells in the new ataxic mutant mouse, pogo.
Neuroscience letters - 17 Nov 2000
Jeong Y G, Hyun B H
Abstract excerpt
The pogo mouse is a new ataxic mutant derived from the Korean wild mouse. The pathological manifestations include difficulty in maintaining normal posture and the inability to walk straight. The ataxia becomes apparent at about 2 weeks of age. Electron microscopic studies of the pogo/pogo homozygous cerebellum, revealed that the ectopic spines emanating from the primary dendrite of Purkinje cells were observed....
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