Article
Humoral and cellular immune responses to the GB virus C/hepatitis G virus envelope 2 protein.
Journal of medical virology - 1 Nov 2000
Lazdina U, Hultgren C, Chen M, Fischler B, Weiland O, Mushahwar I K, Sällberg M
Abstract excerpt
Immune responses to two recombinant envelope 2 (E2) proteins, representing genotypes 1 and 2 of the GB virus C, or the hepatitis G virus (GBV-C/HGV), were studied in mice and in 48 individuals with, or without, chronic, or past GBV-C/HGV infection. Immunised mice developed E2-specific antibodies (mean titres, 1:1,167 to 1:9,360), recognising linear antigenic regions and proliferative and IL-2, IL-6 and gammaIFN...
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