Article
Strain-specific neutralizing antibody responses against human cytomegalovirus envelope glycoprotein N.
Clinical and vaccine immunology : CVI - 1 Jun 2012
Pati Sunil K, Novak Zdenek, Purser Misty, Arora Nitin, Mach Michael, Britt William J, Boppana Suresh B
Abstract excerpt
The human cytomegalovirus (HCMV) gM-gN complex is a major target of virus-neutralizing activity, and gN subtypes induce strain-specific antibodies. However, the biological significance of HCMV gN polymorphisms is not known. Neutralizing antibody responses against HCMV gN recombinant viruses were investigated at study entry in 80 healthy HCMV-seropositive women who were monitored for the appearance of new antibody...
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