Article
Identification of SWI.SNF complex subunit BAF60a as a determinant of the transactivation potential of Fos/Jun dimers.
The Journal of biological chemistry - 26 Jan 2001
Ito T, Yamauchi M, Nishina M, Yamamichi N, Mizutani T, Ui M, Murakami M, Iba H
Abstract excerpt
Fos family proteins form stable heterodimers with Jun family proteins, and each heterodimer shows distinctive transactivating potential for regulating cellular growth, differentiation, and development via AP-1 binding sites. However, the molecular mechanism underlying dimer specificity and the mo...
Topics
- Dimerization
- Mutation
- Protein Binding
- Proto-Oncogene Proteins c-fos
- Proto-Oncogene Proteins c-jun
- Sequence Deletion
- Transcription Factor AP-1
- Transcription Factors
- Transcriptional Activation