Article
Global expression profiling reveals genetic programs underlying the developmental divergence between mouse and human embryogenesis.
BMC genomics - 20 Aug 2013
Xue Lu, Cai Jin-Yang, Ma Jian, Huang Zan, Guo Ming-Xiong, Fu Lie-Zhen, Shi Yun-Bo, Li Wen-Xin
Abstract excerpt
BACKGROUND: Mouse has served as an excellent model for studying human development and diseases due to its similarity to human. Advances in transgenic and knockout studies in mouse have dramatically strengthened the use of this model and significantly improved our understanding of gene function during development in the past few decades. More recently, global gene expression analyses have revealed novel features...
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