Article
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development
15 Apr 2000
Abstract excerpt
Little is known about gene action in the preimplantation events that initiate mammalian development. Based on cDNA collections made from each stage from egg to blastocyst, 25438 3'-ESTs were derived, and represent 9718 genes, half of them novel. Thus, a considerable fraction of mammalian genes is dedicated to embryonic expression. This study reveals profound changes in gene expression that include the transient...
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