Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive chromosomal analysis of human preimplantation embryos using whole genome amplification and single cell comparative genomic hybridization

1 Nov 2000

Abstract excerpt

Analysis of small numbers of chromosomes using interphase fluorescent in-situ hybridization (FISH) probes has revealed that 50% of human preimplantation embryos contain abnormal cells. Detection of high levels of mosaicism with so few probes has led some researchers to extrapolate that a full analysis of all 23 pairs of chromosomes would reveal that all human embryos contain a proportion of abnormal cells....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomal and Genetic Variations
Share to Genomic variations and chromosomal abnormalities
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11044470
DOI: 10.1093/molehr/6.11.1055

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive chromosomal analysis of human preimplantation embryos using whole genome amplification and single cell comparative genomic hybridizationPMID 11044470Read ↗

Chromosome instability is common in human cleavage-stage embryos.Semantic proximity Read ↗

Preimplantation genetic diagnosis and chromosome analysis of blastomeres using comparative genomic hybridizationSemantic proximity Read ↗

Single-cell analysis of human embryos reveals diverse patterns of aneuploidy and mosaicismSemantic proximity Read ↗

Single-cell DNA sequencing reveals a high incidence of chromosomal abnormalities in human blastocystsSemantic proximity Read ↗

Single cell CGH analysis reveals a high degree of mosaicism in human embryos from patients with balanced structural chromosome aberrationsSemantic proximity Read ↗

Preimplantation Genetic Testing for Chromosomal Abnormalities: Aneuploidy, Mosaicism, and Structural RearrangementsSemantic proximity Read ↗

Microarray analysis reveals abnormal chromosomal complements in over 70% of 14 normally developing human embryosSemantic proximity Read ↗

A multi-omics genome-and-transcriptome single-cell atlas of human preimplantation embryogenesis reveals the cellular and molecular impact of chromosome instabilitySemantic proximity Read ↗

Single-cell analysis of human embryos reveals diverse patterns of aneuploidy and mosaicism.Semantic proximity Read ↗

Detailed chromosomal and molecular genetic analysis of single cells by whole genome amplification and comparative genomic hybridisationSemantic proximity Read ↗

Methods for comprehensive chromosome screening of oocytes and embryos: capabilities, limitations, and evidence of validitySemantic proximity Read ↗

Single-cell chromosomal imbalances detection by array CGHSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.