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Repressive and restrictive mesodermal interactions with gut endoderm: possible relation to Meckel’s Diverticulum

15 Nov 2000

Abstract excerpt

The midgut and hindgut endoderm of the mouse embryo give rise to the intestinal epithelium, yet it is not known how the intestinal program is chosen in contrast to other endoderm-derived cell types. Previous tissue explant studies with embryos at 8.5 to 11.5 days gestation (d) showed that when the gut mesoderm is removed from the prospective intestinal endoderm, the endoderm activates the expression of...

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PMID: 11044405
DOI: 10.1242/dev.127.22.4915

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