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Neuronal Apoptosis in Creutzfeldt-Jakob Disease

1 Apr 1999

Abstract excerpt

Neuronal loss is a salient feature of prion diseases; however, its causes and mechanisms are unclear The possibility that it could occur through an apoptotic process has been postulated and is consistent with the lack of inflammation in prion disorders as supported by experimental studies. In order to test this hypothesis in humans, we examined samples of frontal and temporal cerebral cortex, striatum, thalamus,...

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PMID: 10218627
DOI: 10.1097/00005072-199904000-00002

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