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Article

Neuronal Cell Death in Scrapie‐Infected Mice Is Due to Apoptosis

1 Jul 1995

Abstract excerpt

Neuronal loss is a salient yet poorly understood feature in the pathology of transmissible spongiform encephalopathies (prion diseases). Cell culture experiments with neurotoxic prion protein fragments suggest that neuronal cell death in these diseases may be due to apoptosis. To test this hypothesis in vivo we used the in situ end-labeling (ISEL) technique and electron microscopy to study cell death in an...

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Identifiers

PMID: 8520720
DOI: 10.1111/j.1750-3639.1995.tb00597.x

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Neuronal Cell Death in Scrapie‐Infected Mice Is Due to ApoptosisPMID 8520720Read ↗

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