Article
Major strengths and weaknesses of model-free methods.
Advances in genetics - 1 Jan 2001
Goldgar D E
Abstract excerpt
This chapter discusses some of the principal advantages and disadvantages inherent in the use of model-free (MF) methods. The principal advantage is that one does not need to specify, a priori, a genetic model for the trait of interest, which often is not known for many complex phenotypes of interest. On the other hand, as with all nonparametric approaches, use of model-free methods results in reduced power for...
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