Article
Analysis of TNFalpha microsatellites in 35 patients with primary Sjögren's syndrome.
Joint bone spine - 1 Jan 2000
Guggenbuhl P, Veillard E, Quelvenec E, Jego P, Semana G, Jean S, Meadeb J, Chalès G, Perdriger A
Abstract excerpt
OBJECTIVES: Although the cause of Sjögren's syndrome remains unknown, many arguments suggest a role for both environmental and genetic factors. An association with HLA molecules has been established. Other genes on the short arm of chromosome 6 may be involved, most notably the TNF gene, which may be pivotal in the development of the epithelial lesions. METHODS: We investigated TNFalpha microsatellites in 35...
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