Article
Quantitative trait loci (QTL) for lean body mass and body length in MRL/MPJ and SJL/J F(2) mice.
Functional & integrative genomics - 1 Aug 2002
Masinde Godfred L, Li Xinmin, Gu Weikuan, Davidson Heather, Hamilton-Ulland Melanie, Wergedal Jon, Mohan Subburaman, Baylink David J
Abstract excerpt
Studies on the genetic mechanisms involved in the regulation of lean body mass (LBM) in mammals are minimal, although LBM is associated with a competent immune system and an overall good (healthy) body functional status. In this study, we performed a high-density genome-wide scan using 633 (MRL/MPJ x SJL/J) F(2) intercross to identify the quantitative trait loci (QTL) involved in the regulation of LBM. We...
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