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Article

An outbreak of pulmonary mycosis in respiratory burst-deficient (gp91(phox-/-))Mice with concurrent acidophilic macrophage pneumonia.

Journal of comparative pathology - 1 Jan 2000

France M P, Muir D

Abstract excerpt

An outbreak of pulmonary abscessation due to the common environmental fungus Paecilomyces variotii occurred in a colony of gp91(phox-/-)mice, which lack functional NADPH oxidase, the enzyme complex responsible for generating the respiratory burst in phagocytes. Parenchyma surrounding the abscesses showed intense acidophilic macrophage pneumonia, and similar but much milder lesions were present in each of 24...

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PMID: 11032674
DOI: 10.1053/jcpa.2000.0393

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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