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Article

Brain derived neurotrophic factor (BDNF) gene variants association with age at onset and therapeutic response in schizophrenia.

Molecular psychiatry - 1 Sept 2000

Krebs M O, Guillin O, Bourdell M C, Schwartz J C, Olie J P, Poirier M F, Sokoloff P

Abstract excerpt

Schizophrenia is a heterogeneous disease involving genetic and environmental factors. The frequency of structural brain abnormalities or physical anomalies supports a neurodevelopmental etiology, especially in early onset schizophrenia. Brain-Derived-Neurotrophic-Factor (BDNF) is involved in the neurodevelopment of dopaminergic (DA)-related systems and interacts with the meso-limbic DA systems, involved in the...

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Source

Identifiers

PMID: 11032392
DOI: 10.1038/sj.mp.4000749

Genes

BDNF
DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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