Article
The study of BDNF Val66Met polymorphism in Chinese schizophrenic patients.
Progress in neuro-psychopharmacology & biological psychiatry - 16 Aug 2010
Zhou Dong Hao, Yan Quan Zhi, Yan Xiao Mei, Li Cun Bao, Fang Hui, Zheng You Lan, Zhang Chong Xi, Yao Hui Jun, Chen Da Chun, Xiu Mei Hong, Kosten Thomas R, Zhang Xiang Yang
Abstract excerpt
Accumulating evidence showed that brain-derived neurotrophic factor (BDNF) may be involved in the pathophysiology of schizophrenia. Recent studies have reported that the Val66Met polymorphism of the BDNF gene may be associated with susceptibility for schizophrenia and age of onset of this disease, with mix results. In the present study, the BDNF Val66Met gene polymorphism was examined in 387 inpatients (259 men...
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