Article
Bone morphogenetic proteins (BMPs) induce epithelial differentiation of NT2D1 human embryonal carcinoma cells.
The International journal of developmental biology - 1 Aug 2000
Caricasole A, Ward-van Oostwaard D, Zeinstra L, van den Eijnden-van Raaij A, Mummery C
Abstract excerpt
Human embryonal carcinoma (EC) cells represent the stem cells of testicular germ cell tumours (TGCTs) and are morphologically, antigenically and functionally related to the stem cells of early mammalian embryos. Despite the large capacity for differentiation displayed by TGCT stem cells, little is known of the factors controlling their developmental potency. We have analyzed the differentiation elicited in NT2D1...
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